hrp0094p1-171 | Growth Hormone and IGFs B | ESPE2021

Diagnosing growth hormone deficiency - Can a combined arginine and clonidine stimulation test replace two separate tests?

Oron Tal , Krieger Avihu , Yakobovich-Gavan Michal , Tenenbaum Ariel , Diamant Rotem , Phillip Moshe , Lazar Liora ,

Objective: Given a large number of false-positive growth hormone deficiency (GHD) diagnoses from a single GH stimulation test in normal children, two different pharmacological tests, performed on separate days or sequentially, are required. This study aims to assess the reliability and safety of a combined clonidine-arginine stimulation test (CACST).Design: Retrospective, single-center, observational study....